Every player at the 2014 World Cup in Brazil will be required to have a biological profile - sometimes called a biological passport.
Soccer's world governing body, FIFA, is introducing the system as part of the worldwide crackdown on doping.
The biological profile is considered one of the best methods to detect the use of performance-enhancing drugs.
In- and out-of-competition tests would be conducted on all participating players.
FIFA medical officer Michel D'Hooghe says FIFA is developing plans to introduce profiling, including a steroid profile through urine and a blood collections at training camps and games.
Biological profiling is considered one of the most effective methods of detecting the use of performance-enhancing drugs and blood boosters like EPO.
EPO was first tested in FIFA competitions at Korea/Japan 2002.
FIFA is also developing a hormonal profiling project.
World Anti-Doping Agency president John Fahey says, "We are very interested in continuing the work on biological profiles."